strange one brad.
What about taking the battery terminals off for 20 mins (doing a basic reset).
Alternatively, you might need to get the car scanned with VCDS/Vagcom and see if it has any errors.
If you put the windows down, then lock/unlock the car, can you open from the inside (ie, leaning over the window), but not from the outside?
Does opening from the outside 'ever' work? Ie, does it not work 100% of the time? If so, it does sound like the external handle is not 'connected' to the door mechanism anymore.